Characterization and Epitope Mapping of Neutralizing Monoclonal Antibodies Produced by Immunization with Oligomeric Simian Immunodeficiency Virus Envelope Protein

In an attempt to generate broadly cross-reactive, neutralizing monoclonal antibodies (MAbs) to simian immunodeficiency virus (SIV), we compared two immunization protocols using different preparations of oligomeric SIV envelope (Env) glycoproteins. In the first protocol, mice were immunized with solu...

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Autors principals: Edinger, Aimee L., Ahuja, Ména, Sung, Tina, Baxter, Kelly C., Haggarty, Beth, Doms, Robert W., Hoxie, James A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC112323/
https://ncbi.nlm.nih.gov/pubmed/10933700
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