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Effect of Epitope Position on Neutralization by Anti-Human Immunodeficiency Virus Monoclonal Antibody 2F5

The membrane-proximal region of the human immunodeficiency virus type 1 (HIV-1) transmembrane protein (TM) is critical for envelope (Env)-mediated membrane fusion and contains the target for broadly reactive neutralizing antibody 2F5. It has been proposed that 2F5 neutralization might involve intera...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ou, Wu, Lu, Ning, Yu, Sloane S., Silver, Jonathan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395390/
https://ncbi.nlm.nih.gov/pubmed/16474160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.5.2539-2547.2006
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