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An Unrelated Monoclonal Antibody Neutralizes Human Immunodeficiency Virus Type 1 by Binding to an Artificial Epitope Engineered in a Functionally Neutral Region of the Viral Envelope Glycoproteins

Neutralizing antibodies often recognize regions of viral envelope glycoproteins that play a role in receptor binding or other aspects of virus entry. To address whether this is a necessary feature of a neutralizing antibody, we identified the V4 region of the gp120 envelope glycoprotein of human imm...

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Detalhes bibliográficos
Main Authors: Ren, Xinping, Sodroski, Joseph, Yang, Xinzhen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1082744/
https://ncbi.nlm.nih.gov/pubmed/15827176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.9.5616-5624.2005
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