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Introduction of Exogenous Epitopes in the Variable Regions of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein: Effect on Viral Infectivity and the Neutralization Phenotype

In this study we examined whether human immunodeficiency virus type 1 (HIV-1) is equally susceptible to neutralization by a given antibody when the epitope of this antibody is introduced at different positions within the viral envelope glycoprotein (Env). To this end, we introduced two exogenous “ep...

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Détails bibliographiques
Auteurs principaux: Wallace, Aaron, Stamatatos, Leonidas
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715762/
https://ncbi.nlm.nih.gov/pubmed/19494007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00582-09
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