Novel Rabies Virus-Neutralizing Epitope Recognized by Human Monoclonal Antibody: Fine Mapping and Escape Mutant Analysis

Anti-rabies virus immunoglobulin combined with rabies vaccine protects humans from lethal rabies infections. For cost and safety reasons, replacement of the human or equine polyclonal immunoglobulin is advocated, and the use of rabies virus-specific monoclonal antibodies (MAbs) is recommended. We pr...

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Detalhes bibliográficos
Main Authors: Marissen, Wilfred E., Kramer, R. Arjen, Rice, Amy, Weldon, William C., Niezgoda, Michael, Faber, Milosz, Slootstra, Jerry W., Meloen, Rob H., Clijsters-van der Horst, Marieke, Visser, Therese J., Jongeneelen, Mandy, Thijsse, Sandra, Throsby, Mark, de Kruif, John, Rupprecht, Charles E., Dietzschold, Bernhard, Goudsmit, Jaap, Bakker, Alexander B. H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069557/
https://ncbi.nlm.nih.gov/pubmed/15795253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.8.4672-4678.2005
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