Novel Rabies Virus-Neutralizing Epitope Recognized by Human Monoclonal Antibody: Fine Mapping and Escape Mutant Analysis

Anti-rabies virus immunoglobulin combined with rabies vaccine protects humans from lethal rabies infections. For cost and safety reasons, replacement of the human or equine polyclonal immunoglobulin is advocated, and the use of rabies virus-specific monoclonal antibodies (MAbs) is recommended. We pr...

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Autores principales: Marissen, Wilfred E., Kramer, R. Arjen, Rice, Amy, Weldon, William C., Niezgoda, Michael, Faber, Milosz, Slootstra, Jerry W., Meloen, Rob H., Clijsters-van der Horst, Marieke, Visser, Therese J., Jongeneelen, Mandy, Thijsse, Sandra, Throsby, Mark, de Kruif, John, Rupprecht, Charles E., Dietzschold, Bernhard, Goudsmit, Jaap, Bakker, Alexander B. H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069557/
https://ncbi.nlm.nih.gov/pubmed/15795253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.8.4672-4678.2005
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