Modulation of DNA Vaccine-Elicited CD8(+) T-Lymphocyte Epitope Immunodominance Hierarchies

Generating broad cellular immune responses against a diversity of viral epitopes is a major goal of current vaccine strategies for human immunodeficiency virus type 1 (HIV-1) and other pathogens. Virus-specific CD8(+) T-lymphocyte responses, however, are often highly focused on a very limited number...

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Bibliographic Details
Main Authors: Liu, Jinyan, Ewald, Bonnie A., Lynch, Diana M., Nanda, Anjali, Sumida, Shawn M., Barouch, Dan H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1676306/
https://ncbi.nlm.nih.gov/pubmed/17005652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01348-06
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