TLR4 Ligands Augment Antigen-Specific CD8(+) T Lymphocyte Responses Elicited by a Viral Vaccine Vector

Toll-like receptor (TLR) ligands are critical activators of innate immunity and are being developed as vaccine adjuvants. However, their utility in conjunction with viral vector-based vaccines remains unclear. In this study, we evaluated the impact of a variety of TLR ligands on antigen-specific CD8...

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Bibliographische Detailangaben
Hauptverfasser: Rhee, Elizabeth G., Kelley, R. Phelps, Agarwal, Isha, Lynch, Diana M., La Porte, Annalena, Simmons, Nathaniel L., Clark, Sarah L., Barouch, Dan H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937821/
https://ncbi.nlm.nih.gov/pubmed/20631129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00928-10
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