Alternative Serotype Adenovirus Vaccine Vectors Elicit Memory T Cells with Enhanced Anamnestic Capacity Compared to Ad5 Vectors

The failure of the adenovirus serotype 5 (Ad5) vector-based human immunodeficiency virus type 1 (HIV-1) vaccine in the STEP study has led to the development of adenovirus vectors derived from alternative serotypes, such as Ad26, Ad35, and Ad48. We have recently demonstrated that vaccines using alter...

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Detalhes bibliográficos
Main Authors: Penaloza-MacMaster, Pablo, Provine, Nicholas M., Ra, Joshua, Borducchi, Erica N., McNally, Anna, Simmons, Nathaniel L., Iampietro, Mark J., Barouch, Dan H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554181/
https://ncbi.nlm.nih.gov/pubmed/23152535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02058-12
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