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Effects of protein stability and structure on substrate processing by the ClpXP unfolding and degradation machine

ClpXP is an ATP-dependent protease that denatures native proteins and translocates the denatured polypeptide into an interior peptidase chamber for degradation. To address the mechanism of these processes, Arc repressor variants with dramatically different stabilities and unfolding half-lives varyin...

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Hlavní autoři: Burton, Randall E., Siddiqui, Samia M., Kim, Yong-In, Baker, Tania A., Sauer, Robert T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC150209/
https://ncbi.nlm.nih.gov/pubmed/11406586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.12.3092
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