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Effects of protein stability and structure on substrate processing by the ClpXP unfolding and degradation machine

ClpXP is an ATP-dependent protease that denatures native proteins and translocates the denatured polypeptide into an interior peptidase chamber for degradation. To address the mechanism of these processes, Arc repressor variants with dramatically different stabilities and unfolding half-lives varyin...

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Bibliographische Detailangaben
Hauptverfasser: Burton, Randall E., Siddiqui, Samia M., Kim, Yong-In, Baker, Tania A., Sauer, Robert T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC150209/
https://ncbi.nlm.nih.gov/pubmed/11406586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.12.3092
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