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Effects of protein stability and structure on substrate processing by the ClpXP unfolding and degradation machine
ClpXP is an ATP-dependent protease that denatures native proteins and translocates the denatured polypeptide into an interior peptidase chamber for degradation. To address the mechanism of these processes, Arc repressor variants with dramatically different stabilities and unfolding half-lives varyin...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150209/ https://ncbi.nlm.nih.gov/pubmed/11406586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.12.3092 |
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