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Partitioning between unfolding and release of native domains during ClpXP degradation determines substrate selectivity and partial processing
Energy-dependent proteases, such as ClpXP, are responsible for the regulated destruction of proteins in all cells. AAA+ ATPases in these proteases bind protein substrates and power their mechanical denaturation and subsequent translocation into a secluded degradation chamber where polypeptide cleava...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC547888/ https://ncbi.nlm.nih.gov/pubmed/15671177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409634102 |
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