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Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes

γ-Secretase-dependent regulated intramembrane proteolysis of amyloid precursor protein (APP) releases the APP intracellular domain (AICD). The question of whether this domain, like the Notch intracellular domain, is involved in nuclear signalling is highly controversial. Although some reports sugges...

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מידע ביבליוגרפי
Main Authors: Hébert, Sébastien S, Serneels, Lutgarde, Tolia, Alexandra, Craessaerts, Katleen, Derks, Carmen, Filippov, Mikhail A, Müller, Ulrike, De Strooper, Bart
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500829/
https://ncbi.nlm.nih.gov/pubmed/16729020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400704
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