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Alteration of Escherichia coli Topoisomerase IV to Novobiocin Resistance
DNA gyrase and topoisomerase IV (topo IV) are the two essential type II topoisomerases of Escherichia coli. Gyrase is responsible for maintaining negative supercoiling of the bacterial chromosome, whereas topo IV's primary role is in disentangling daughter chromosomes following DNA replication....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149342/ https://ncbi.nlm.nih.gov/pubmed/12604525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.3.941-947.2003 |
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