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Alteration of Escherichia coli Topoisomerase IV to Novobiocin Resistance

DNA gyrase and topoisomerase IV (topo IV) are the two essential type II topoisomerases of Escherichia coli. Gyrase is responsible for maintaining negative supercoiling of the bacterial chromosome, whereas topo IV's primary role is in disentangling daughter chromosomes following DNA replication....

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Bibliografische gegevens
Hoofdauteurs: Hardy, Christine D., Cozzarelli, Nicholas R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC149342/
https://ncbi.nlm.nih.gov/pubmed/12604525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.3.941-947.2003
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