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The mechanism of type IA topoisomerases

The topology of cellular DNA is carefully controlled by enzymes called topoisomerases. By using single-molecule techniques, we monitored the activity of two type IA topoisomerases in real time under conditions in which single relaxation events were detected. The strict one-at-a-time removal of super...

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Autori principali: Dekker, N. H., Rybenkov, V. V., Duguet, M., Crisona, N. J., Cozzarelli, N. R., Bensimon, D., Croquette, V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC129409/
https://ncbi.nlm.nih.gov/pubmed/12167668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.132378799
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