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Alteration of Escherichia coli Topoisomerase IV to Novobiocin Resistance
DNA gyrase and topoisomerase IV (topo IV) are the two essential type II topoisomerases of Escherichia coli. Gyrase is responsible for maintaining negative supercoiling of the bacterial chromosome, whereas topo IV's primary role is in disentangling daughter chromosomes following DNA replication....
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2003
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149342/ https://ncbi.nlm.nih.gov/pubmed/12604525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.3.941-947.2003 |
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