Stochastic, stage-specific mechanisms account for the variegation of a human globin transgene.

The random insertion of transgenes into the genomic DNA of mice usually leads to widely variable levels of expression in individual founder lines. To study the mechanisms that cause variegation, we designed a transgene that we expected to variegate, which consisted of a beta-globin locus control reg...

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Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Nucleic Acids Res
Prif Awduron:	Graubert, T A, Hug, B A, Wesselschmidt, R, Hsieh, C L, Ryan, T M, Townes, T M, Ley, T J
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Oxford University Press 1998
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9611227/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.12.2849
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