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Stochastic, stage-specific mechanisms account for the variegation of a human globin transgene.

The random insertion of transgenes into the genomic DNA of mice usually leads to widely variable levels of expression in individual founder lines. To study the mechanisms that cause variegation, we designed a transgene that we expected to variegate, which consisted of a beta-globin locus control reg...

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Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Graubert, T A, Hug, B A, Wesselschmidt, R, Hsieh, C L, Ryan, T M, Townes, T M, Ley, T J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147660/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9611227/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.12.2849
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