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Analysis of the human alpha-globin gene cluster in transgenic mice.

A 350-bp segment of DNA associated with an erythroid-specific DNase I-hypersensitive site (HS-40), upstream of the alpha-globin gene cluster, has been identified as the major tissue-specific regulator of the alpha-globin genes. However, this element does not direct copy number-dependent or developme...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Sharpe, J A, Wells, D J, Whitelaw, E, Vyas, P, Higgs, D R, Wood, W G
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47962/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248238/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.11262
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