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Variegated expression of a globin transgene correlates with chromatin accessibility but not methylation status.

There are now many mammalian examples in which single cell assays of transgene activity have revealed variegated patterns of expression. We have previously reported that transgenes in which globin regulatory elements drive the lacZ reporter gene exhibit variegated expression patterns in mouse erythr...

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Sonraí Bibleagrafaíochta
Main Authors: Garrick, D, Sutherland, H, Robertson, G, Whitelaw, E
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1996
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC146354/
https://ncbi.nlm.nih.gov/pubmed/9016659
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