Variegated expression of a globin transgene correlates with chromatin accessibility but not methylation status.

There are now many mammalian examples in which single cell assays of transgene activity have revealed variegated patterns of expression. We have previously reported that transgenes in which globin regulatory elements drive the lacZ reporter gene exhibit variegated expression patterns in mouse erythr...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Garrick, D, Sutherland, H, Robertson, G, Whitelaw, E
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 1996
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146354/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016659/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.24.4902
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