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Site-specific targeting of aflatoxin adduction directed by triple helix formation in the major groove of oligodeoxyribonucleotides.

The targeted adduction of aflatoxin B1- exo -8,9-epoxide (AFB1- exo -8,9-epoxide) to a specific guanine within an oligodeoxyribonucleotide containing multiple guanines was achieved using a DNA triplex to control sequence selectivity. The oligodeoxyribonucleotide d(AGAGAAGATTTTCTTCTCTTTTTTTTCTCTT), d...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Jones, W R, Stone, M P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147363/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9461470/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.4.1070
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