Sequence-specific recognition of the major groove of DNA by oligodeoxynucleotides via triple helix formation. Footprinting studies.

Homopyrimidine oligodeoxynucleotides recognize the major groove of the DNA double helix at homopurine.homopyrimidine sequences by forming local triple helices. The oligonucleotide is bound parallel to the homopurine strand of the duplex. This binding can be revealed by a footprinting technique using...

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Bibliographic Details
Main Authors: François, J C, Saison-Behmoaras, T, Hélène, C
Format: Artigo
Language:Inglês
Published: 1988
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC339056/
https://ncbi.nlm.nih.gov/pubmed/3211742
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