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Triple-helix formation by alpha oligodeoxynucleotides and alpha oligodeoxynucleotide-intercalator conjugates.

Base-pair sequences in double-stranded DNA can be recognized by homopyrimidine oligonucleotides that bind to the major groove at homopurine.homopyrimidine sequences thereby forming a local triple helix. To make oligodeoxynucleotides resistant to nucleases, we replaced the natural (beta) anomers of t...

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Detalles Bibliográficos
Main Authors: Sun, J S, Giovannangeli, C, François, J C, Kurfurst, R, Montenay-Garestier, T, Asseline, U, Saison-Behmoaras, T, Thuong, N T, Hélène, C
Formato: Artigo
Idioma:Inglês
Publicado: 1991
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC52014/
https://ncbi.nlm.nih.gov/pubmed/2068079
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