Triple-helix formation by alpha oligodeoxynucleotides and alpha oligodeoxynucleotide-intercalator conjugates.

Base-pair sequences in double-stranded DNA can be recognized by homopyrimidine oligonucleotides that bind to the major groove at homopurine.homopyrimidine sequences thereby forming a local triple helix. To make oligodeoxynucleotides resistant to nucleases, we replaced the natural (beta) anomers of t...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sun, J S, Giovannangeli, C, François, J C, Kurfurst, R, Montenay-Garestier, T, Asseline, U, Saison-Behmoaras, T, Thuong, N T, Hélène, C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52014/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2068079/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.14.6023
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