Specific inhibition of transcription by triple helix-forming oligonucleotides.
Homopyrimidine oligonucleotides bind to the major groove of a complementary homopyrimidine.homopurine stretch by triple helix formation. The bla gene from transposon Tn3 contains a homopyrimidine.homopurine sequence of 13 base pairs located just downstream of the RNA polymerase binding site. A 13-me...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48267/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1731320/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.2.504 |
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