Specific inhibition of transcription by triple helix-forming oligonucleotides.
Homopyrimidine oligonucleotides bind to the major groove of a complementary homopyrimidine.homopurine stretch by triple helix formation. The bla gene from transposon Tn3 contains a homopyrimidine.homopurine sequence of 13 base pairs located just downstream of the RNA polymerase binding site. A 13-me...
Sábháilte in:
| Foilsithe in: | Proc Natl Acad Sci U S A |
|---|---|
| Príomhchruthaitheoirí: | , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
National Academy of Sciences
1992
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| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48267/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1731320/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.2.504 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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