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Specific inhibition of transcription by triple helix-forming oligonucleotides.

Homopyrimidine oligonucleotides bind to the major groove of a complementary homopyrimidine.homopurine stretch by triple helix formation. The bla gene from transposon Tn3 contains a homopyrimidine.homopurine sequence of 13 base pairs located just downstream of the RNA polymerase binding site. A 13-me...

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Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Duval-Valentin, G, Thuong, N T, Hélène, C
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 1992
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48267/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1731320/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.2.504
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