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Oligodeoxynucleotide-directed photo-induced cross-linking of HIV proviral DNA via triple-helix formation.

The HIV proviral genome contains two copies of a 16 bp homopurine.homopyrimidine sequence which overlaps the recognition and cleavage site of the Dra I restriction enzyme. Psoralen was attached to the 16-mer homopyrimidine oligonucleotide, d5'(TTTTCT-TTTCCCCCCT)3', which forms a triple hel...

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Bibliographische Detailangaben
Hauptverfasser: Giovannangéli, C, Thuong, N T, Hélène, C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC334136/
https://ncbi.nlm.nih.gov/pubmed/1508719
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