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Oligodeoxynucleotide-directed photo-induced cross-linking of HIV proviral DNA via triple-helix formation.
The HIV proviral genome contains two copies of a 16 bp homopurine.homopyrimidine sequence which overlaps the recognition and cleavage site of the Dra I restriction enzyme. Psoralen was attached to the 16-mer homopyrimidine oligonucleotide, d5'(TTTTCT-TTTCCCCCCT)3', which forms a triple hel...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1992
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC334136/ https://ncbi.nlm.nih.gov/pubmed/1508719 |
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