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Oligodeoxynucleotide-directed photo-induced cross-linking of HIV proviral DNA via triple-helix formation.

The HIV proviral genome contains two copies of a 16 bp homopurine.homopyrimidine sequence which overlaps the recognition and cleavage site of the Dra I restriction enzyme. Psoralen was attached to the 16-mer homopyrimidine oligonucleotide, d5'(TTTTCT-TTTCCCCCCT)3', which forms a triple helix with th...

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Pubblicato in:Nucleic Acids Res
Autori principali: Giovannangéli, C, Thuong, N T, Hélène, C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1992
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1508719/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.16.4275
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