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Activated Cdc42/Rac reconstitutes FcɛRI-mediated Ca(2+) mobilization and degranulation in mutant RBL mast cells
Antigen stimulation of mast cells via FcɛRI, the high-affinity receptor for IgE, triggers a signaling cascade that requires Ca(2+) mobilization for exocytosis of secretory granules during an allergic response. This study investigates critical signaling components by using mutant RBL mast cells that...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC14724/ https://ncbi.nlm.nih.gov/pubmed/11158610 |
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