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Mutant RBL Mast Cells Defective in FcεRI Signaling and Lipid Raft Biosynthesis Are Reconstituted by Activated Rho-family GTPases

Characterization of defects in a variant subline of RBL mast cells has revealed a biochemical event proximal to IgE receptor (FcεRI)-stimulated tyrosine phosphorylation that is required for multiple functional responses. This cell line, designated B6A4C1, is deficient in both FcεRI-mediated degranul...

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Detalhes bibliográficos
Main Authors: Field, Kenneth A., Apgar, John R., Hong-Geller, Elizabeth, Siraganian, Reuben P., Baird, Barbara, Holowka, David
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15022/
https://ncbi.nlm.nih.gov/pubmed/11029062
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