Mutant RBL Mast Cells Defective in FcεRI Signaling and Lipid Raft Biosynthesis Are Reconstituted by Activated Rho-family GTPases

Characterization of defects in a variant subline of RBL mast cells has revealed a biochemical event proximal to IgE receptor (FcεRI)-stimulated tyrosine phosphorylation that is required for multiple functional responses. This cell line, designated B6A4C1, is deficient in both FcεRI-mediated degranul...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Field, Kenneth A., Apgar, John R., Hong-Geller, Elizabeth, Siraganian, Reuben P., Baird, Barbara, Holowka, David
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 2000
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15022/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11029062/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.10.3661
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