FcɛRI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane

The aggregation of high affinity IgE receptors (Fcɛ receptor I [FcɛRI]) on mast cells is potent stimulus for the release of inflammatory and allergic mediators from cytoplasmic granules. However, the molecular mechanism of degranulation has not yet been established. It is still unclear how FcɛRI-med...

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Detalhes bibliográficos
Main Authors: Nishida, Keigo, Yamasaki, Satoru, Ito, Yukitaka, Kabu, Koki, Hattori, Kotaro, Tezuka, Tohru, Nishizumi, Hirofumi, Kitamura, Daisuke, Goitsuka, Ryo, Geha, Raif S., Yamamoto, Tadashi, Yagi, Takeshi, Hirano, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171390/
https://ncbi.nlm.nih.gov/pubmed/15998803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200501111
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