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FcɛRI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane

The aggregation of high affinity IgE receptors (Fcɛ receptor I [FcɛRI]) on mast cells is potent stimulus for the release of inflammatory and allergic mediators from cytoplasmic granules. However, the molecular mechanism of degranulation has not yet been established. It is still unclear how FcɛRI-med...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Nishida, Keigo, Yamasaki, Satoru, Ito, Yukitaka, Kabu, Koki, Hattori, Kotaro, Tezuka, Tohru, Nishizumi, Hirofumi, Kitamura, Daisuke, Goitsuka, Ryo, Geha, Raif S., Yamamoto, Tadashi, Yagi, Takeshi, Hirano, Toshio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171390/
https://ncbi.nlm.nih.gov/pubmed/15998803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200501111
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