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Partnering between monomers of cyclooxygenase-2 homodimers
Prostaglandin endoperoxide H synthases (PGHSs) 1 and 2 convert arachidonic acid to prostaglandin H(2) in the committed step of prostanoid biosynthesis. These enzymes are pharmacological targets of nonsteroidal antiinflammatory drugs and cyclooxygenase (COX) 2 inhibitors. Although PGHSs function as h...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458845/ https://ncbi.nlm.nih.gov/pubmed/16606823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601805103 |
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