Cyclooxygenase Allosterism, Fatty Acid-mediated Cross-talk between Monomers of Cyclooxygenase Homodimers

Prostaglandin endoperoxide H synthases (PGHSs) 1 and 2, also known as cyclooxygenases (COXs), catalyze the oxygenation of arachidonic acid (AA) in the committed step in prostaglandin (PG) biosynthesis. PGHSs are homodimers that display half of sites COX activity with AA; thus, PGHSs function as conf...

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Detaylı Bibliyografya
Asıl Yazarlar: Yuan, Chong, Sidhu, Ranjinder S., Kuklev, Dmitry V., Kado, Yuji, Wada, Masayuki, Song, Inseok, Smith, William L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2009
Konular:
Enzyme Catalysis and Regulation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665059/
https://ncbi.nlm.nih.gov/pubmed/19218248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808634200
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