Partnering between monomers of cyclooxygenase-2 homodimers

Prostaglandin endoperoxide H synthases (PGHSs) 1 and 2 convert arachidonic acid to prostaglandin H(2) in the committed step of prostanoid biosynthesis. These enzymes are pharmacological targets of nonsteroidal antiinflammatory drugs and cyclooxygenase (COX) 2 inhibitors. Although PGHSs function as h...

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Bibliografske podrobnosti
Main Authors: Yuan, Chong, Rieke, Caroline Jill, Rimon, Gilad, Wingerd, Byron A., Smith, William L.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458845/
https://ncbi.nlm.nih.gov/pubmed/16606823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601805103
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