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A transgenic approach for RNA interference-based genetic screening in mice

Genetic screening is the most powerful method through which to uncover gene function. It has been applied very successfully in lower organisms but seldom attempted in mammalian species because of their long generation time. In this study, we exploit RNA interference (RNAi) for its potential use in g...

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Autori principali: Peng, Shaohua, York, J. Philippe, Zhang, Pumin
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413752/
https://ncbi.nlm.nih.gov/pubmed/16461920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511034103
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