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A universal transgene silencing method based on RNA interference

Inducible gene expression systems have contributed significantly to the understanding of molecular regulatory networks. Here we describe a simple and powerful RNA interference-based method that can silence the expression of any transgene. We first used an IRES bicistronic lentiviral vector and showe...

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Detalhes bibliográficos
Main Authors: Mangeot, Philippe-Emmanuel, Cosset, François-Loïc, Colas, Pierre, Mikaelian, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC484202/
https://ncbi.nlm.nih.gov/pubmed/15249598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh105
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