Tissue-specific and reversible RNA interference in transgenic mice

Genetically engineered mice provide powerful tools for understanding mammalian gene function. These models traditionally rely on gene overexpression from transgenes or targeted, irreversible gene mutation. By adapting the tetracycline (tet)-responsive system previously used for gene overexpression,...

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Vydáno v:Nat Genet
Hlavní autoři: Dickins, Ross A, McJunkin, Katherine, Hernando, Eva, Premsrirut, Prem K, Krizhanovsky, Valery, Burgess, Darren J, Yong Kim, Sang, Cordon-Cardo, Carlos, Zender, Lars, Hannon, Gregory J, Lowe, Scott W
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595852/
https://ncbi.nlm.nih.gov/pubmed/17572676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng2045
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