Tissue-specific and reversible RNA interference in transgenic mice

Genetically engineered mice provide powerful tools for understanding mammalian gene function. These models traditionally rely on gene overexpression from transgenes or targeted, irreversible gene mutation. By adapting the tetracycline (tet)-responsive system previously used for gene overexpression,...

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Publicat a:Nat Genet
Autors principals: Dickins, Ross A, McJunkin, Katherine, Hernando, Eva, Premsrirut, Prem K, Krizhanovsky, Valery, Burgess, Darren J, Yong Kim, Sang, Cordon-Cardo, Carlos, Zender, Lars, Hannon, Gregory J, Lowe, Scott W
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595852/
https://ncbi.nlm.nih.gov/pubmed/17572676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng2045
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