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Tissue-specific and reversible RNA interference in transgenic mice
Genetically engineered mice provide powerful tools for understanding mammalian gene function. These models traditionally rely on gene overexpression from transgenes or targeted, irreversible gene mutation. By adapting the tetracycline (tet)-responsive system previously used for gene overexpression,...
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| Publicado no: | Nat Genet |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4595852/ https://ncbi.nlm.nih.gov/pubmed/17572676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng2045 |
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