Tissue-specific and reversible RNA interference in transgenic mice

Genetically engineered mice provide powerful tools for understanding mammalian gene function. These models traditionally rely on gene overexpression from transgenes or targeted, irreversible gene mutation. By adapting the tetracycline (tet)-responsive system previously used for gene overexpression,...

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Bibliografiset tiedot
Julkaisussa:Nat Genet
Päätekijät: Dickins, Ross A, McJunkin, Katherine, Hernando, Eva, Premsrirut, Prem K, Krizhanovsky, Valery, Burgess, Darren J, Yong Kim, Sang, Cordon-Cardo, Carlos, Zender, Lars, Hannon, Gregory J, Lowe, Scott W
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595852/
https://ncbi.nlm.nih.gov/pubmed/17572676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng2045
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