A pipeline for the generation of shRNA transgenic mice

RNA interference (RNAi) is an extremely effective tool for studying gene function in almost all metazoan and eukaryotic model systems. RNAi in mice, through the expression of short hairpin RNA s (shRNA s), offers something not easily achieved with traditional genetic approaches—inducible and reversi...

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Main Authors: Dow, Lukas E, Premsrirut, Prem K, Zuber, Johannes, Fellmann, Christof, McJunkin, Katherine, Miething, Cornelius, Park, Youngkyu, Dickins, Ross A, Hannon, Gregory J, Lowe, Scott W
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724521/
https://ncbi.nlm.nih.gov/pubmed/22301776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2011.446
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