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A pipeline for the generation of shRNA transgenic mice

RNA interference (RNAi) is an extremely effective tool for studying gene function in almost all metazoan and eukaryotic model systems. RNAi in mice, through the expression of short hairpin RNA s (shRNA s), offers something not easily achieved with traditional genetic approaches—inducible and reversi...

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Bibliografske podrobnosti
Main Authors: Dow, Lukas E, Premsrirut, Prem K, Zuber, Johannes, Fellmann, Christof, McJunkin, Katherine, Miething, Cornelius, Park, Youngkyu, Dickins, Ross A, Hannon, Gregory J, Lowe, Scott W
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724521/
https://ncbi.nlm.nih.gov/pubmed/22301776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2011.446
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