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Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi

Short hairpin RNAs (shRNAs) are versatile tools for analyzing loss-of-function phenotypes in vitro and in vivo(1). However, their use for studying genes involved in proliferation and survival, which are potential therapeutic targets in cancer and other diseases, is confounded by the strong selective...

詳細記述

保存先:
書誌詳細
主要な著者: Zuber, Johannes, McJunkin, Katherine, Fellmann, Christof, Dow, Lukas E, Taylor, Meredith J, Hannon, Gregory J, Lowe, Scott W
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394154/
https://ncbi.nlm.nih.gov/pubmed/21131983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1720
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