Functional identification of optimized RNAi triggers using a massively parallel Sensor assay

Short hairpin RNAs (shRNAs) provide powerful experimental tools by enabling stable and regulated gene silencing through programming of endogenous microRNA pathways. Since requirements for efficient shRNA biogenesis and target suppression are largely unknown, many predicted shRNAs fail to efficiently...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Fellmann, Christof, Zuber, Johannes, McJunkin, Katherine, Chang, Kenneth, Malone, Colin D., Dickins, Ross A., Xu, Qikai, Hengartner, Michael O., Elledge, Stephen J., Hannon, Gregory J., Lowe, Scott W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130540/
https://ncbi.nlm.nih.gov/pubmed/21353615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.02.008
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller