Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi

Short hairpin RNAs (shRNAs) are versatile tools for analyzing loss-of-function phenotypes in vitro and in vivo(1). However, their use for studying genes involved in proliferation and survival, which are potential therapeutic targets in cancer and other diseases, is confounded by the strong selective...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Zuber, Johannes, McJunkin, Katherine, Fellmann, Christof, Dow, Lukas E, Taylor, Meredith J, Hannon, Gregory J, Lowe, Scott W
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394154/
https://ncbi.nlm.nih.gov/pubmed/21131983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1720
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker