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Tissue-specific and reversible RNA interference in transgenic mice
Genetically engineered mice provide powerful tools for understanding mammalian gene function. These models traditionally rely on gene overexpression from transgenes or targeted, irreversible gene mutation. By adapting the tetracycline (tet)-responsive system previously used for gene overexpression,...
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| Udgivet i: | Nat Genet |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4595852/ https://ncbi.nlm.nih.gov/pubmed/17572676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng2045 |
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