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A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression

RNAi is proving to be a powerful experimental tool for the functional annotation of mammalian genomes. The full potential of this technology will be realized through development of approaches permitting regulated manipulation of endogenous gene expression with coordinated reexpression of exogenous t...

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Detalhes bibliográficos
Main Authors: Shin, Kum-Joo, Wall, Estelle A., Zavzavadjian, Joelle R., Santat, Leah A., Liu, Jamie, Hwang, Jong-Ik, Rebres, Robert, Roach, Tamara, Seaman, William, Simon, Melvin I., Fraser, Iain D. C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557799/
https://ncbi.nlm.nih.gov/pubmed/16945906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606179103
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